Abstract: Drought warning water level (flow) is an important index to determine the drought warning level of rivers, lakes and reservoirs, and an important basis to start the drought emergency response. Taking Boluo hydrologic station in the Dongjiang River Basin as an example, a study was conducted on the determination of drought warning flow. Based on the ecological flow guarantee objectives of key rivers and lakes, the implementation plan of ecological flow guarantee, the water scheduling plan, and the comprehensive planning of Dongjiang River Basin, the water demands for living , agriculture, shipping, and ecology were selected as the main analysis factors. Combined with the actual water inflow during the annual dry season from 2008 to 2021, the drought warning flow of Boluo Station was determined to be 256 m³/s, and the drought warning period was from October of the current year to March of the next year. The rationality of this achievement is analyzed from different angles, and the next work is considered.