Abstract: In 2022, Nanjing City experienced a severe drought, and the Shijiu Lake area suffered from severe water shortage. In order to effectively alleviate the impact of drought, Nanjing has carried out emergency water replenishment in the Shijiu Lake area from the Qinhuai River, with a total of 55.671 million m³ of water replenished. This article analyzes the feasibility and specific implementation process of emergency water replenishment for drought resistance, and analyzes the main problems in terms of water source and water quality assurance. Suggestions and measures are proposed to accelerate the construction of modern water networks, enhance the guarantee ability of water replenishment sources, and strengthen the guarantee of lake water quality standards. It can provide reference for future emergency water replenishment for drought resistance in Nanjing.